No it would affect market prices negatively. If 1 nature is worth 300 gp, and a rune arrow is worth 460 alched. the difference would be 160 gp x1000. Now you're allowing those 999 other runes to go unused and you are netting that 460k without paying the price of the nature runes.

Is anyone in favor of having stacked items high alched at one once with one spell? 

Example:

1 rune arrow I believe high alchs at 400gp.  If you have 1000 and use 1 high alch spell you would get 400k. 

This wouldn't be the same for noted items.

It would be an easy way to make fast money without having to use a ton of nature runes and a ton of time.

Sounds like you are Just been lazy.. like runeknights example just proves how negative the idea as a whole is..

-1 but should batch

Hell no.